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Observed reactions include: Injection-Site Reactions Pain at injection site10,11 Bruising/Contusion6 Hematoma11 Skin / Allergic Rash8 Hypersensitivity reaction12 Dermatitis7 Systemic Urine discoloration (red)9 Across the clinical studies reviewed, no drug-related serious adverse reactions were identified, and only mild and transient adverse events were observed