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Fatigue and tiredness are listed as common adverse reactions in the Summary of Product Characteristics (SmPC) for both semaglutide (Wegovy) and liraglutide (Saxenda) as approved by the Medicines and Healthcare products Regulatory Agency (MHRA)
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Since CagriSema is still in development, there is no approved dosing schedule, and it should be used only within an authorized clinical trial or exactly as a healthcare provider prescribes